Experiencia en mucormicosis Hospital Clínico Universidad de Chile

Authors

  • Eduardo Fernández P Hospital Clínico Universidad de Chile. Departamento de Cirugía
  • María Dünner P. Universidad de Chile
  • Carola Mandiola G. Universidad de Chile
  • Marla Silva C. Universidad de Chile

Abstract

We made a review of the clinical and pathological findings and the treatment in 12 patients presenting mucormycosis in the Clinical Hospital of the University of Chile between 1990 and 2004. Of the whole studied patients, 7 were men and 5 women. The average age was 54 years, with a range from 29 to 79 years. The diagnosis of mucormycosis was performed by biopsy in 10 patients and by direct study in 2 patients. The predisposing factors in the studied patients were: Diabetes Mellitus, HIV at AIDS stage and hematological diseases in oncologic treatment. The histology demonstrated necrosis and infarction with blood vessels invasion and mycotic thrombosis. All the studied patients received treatment with Anphotericine B and 6 required surgical intervention. Of the total of 12 patients, 4 died (33%) and 8 remain alive (66%).

Keywords:

Mucormicosis/diagnóstico, Mucormicosis/epidemiología, Cigomicosis/diagnóstico, Cigomicosis/epidemiología, Comorbilidad, Chile/epidemiología, Infecciones por VIH/epidemiología